Full spectrum vs broad spectrum vs isolate CBD: what's the difference?

26/09/2026
10 ml Formula Swiss full-spectrum CBD oil against a stone, its batch label showing CBD 5.31% and THC 0.16%

Full-spectrum CBD keeps the hemp plant's natural range of cannabinoids, including traces of THC. Broad-spectrum CBD also contains several cannabinoids, but it is THC-free. CBD isolate is purified CBD on its own. Choose full-spectrum for the whole-plant profile and broad-spectrum if you want no THC. Either way, check the batch certificate.

Key facts

Full spectrum
CBD plus other hemp cannabinoids such as CBG, CBC and CBN, with natural traces of THC. Our full-spectrum oils have a THC specification under 0.2%.
Broad spectrum
CBD plus other cannabinoids, without THC. Our THC-free oils have a 0% THC specification, and their batch reports show no detectable THC.
Isolate
CBD only, usually as a white crystalline powder. No other cannabinoids.
How to tell them apart
The certificate of analysis. The THC line and the list of other cannabinoids show which type you have.
Our range
Most of our classic oils come in a full-spectrum and a THC-free version. RAW oils are full spectrum. Of the 30 ml blends, Zermatt Balance and St. Moritz Restore are full spectrum, and Lugano Clarity and Lucerne Calm are THC-free.
How we make them
Every production batch is tested, and we publish the certificates of analysis, so you can check the type on each report.

"Full spectrum", "broad spectrum" and "isolate" describe what is in the extract besides CBD. This guide explains the three types, shows the real cannabinoid profiles of our current oils, sums up what research says about the entourage effect, and helps you choose. Our oils are sold as cosmetics for use on the skin. Always follow the directions on your label.

What is the difference between full spectrum, broad spectrum and isolate CBD?

The three types of CBD extract at a glance
Full spectrum Broad spectrum Isolate
CBD Yes Yes Yes, on its own
Other cannabinoids (CBG, CBC, CBN and others) Yes Yes No
THC Natural traces (ours: under 0.2%) None (ours: not detected) None
Entourage effect possible? Yes, in theory Yes, in theory, without THC No, single compound
A good fit if You want the whole-plant profile You want several cannabinoids and no THC You want CBD alone

These are industry terms rather than legal categories. A European study of 14 CBD oils found wide differences in cannabinoid profiles between products, and 9 of the 14 differed notably from their declared CBD content (Pavlovic et al., 2018). The label tells you the type. The batch certificate shows what is actually in the bottle.

What is full-spectrum CBD oil?

A full-spectrum extract keeps the cannabinoids that the hemp plant makes alongside CBD. Besides CBD, these include CBG (cannabigerol), CBC (cannabichromene), CBN (cannabinol), CBDV (cannabidivarin) and a natural trace of THC. Hemp extracts also carry terpenes, the aroma compounds of the plant.

CO₂ extraction equipment in Formula Swiss's production in Switzerland
CO₂ extraction equipment in our production in Switzerland.

Our full-spectrum oils have a THC specification under 0.2%, and every published report is below that. Each oil's THC value is printed on the label, with the batch number.

Our two full-spectrum 30 ml blends go further. Zermatt Balance combines CBD, CBG, CBN, CBC and CBDA, and St. Moritz Restore combines CBD, CBG and CBC. You can see those cannabinoids on their current reports in the table below. If you want to read about the individual compounds, see our guides to CBG and CBN.

What is broad-spectrum CBD, and is it THC-free?

Broad-spectrum CBD keeps CBD and other cannabinoids, but without THC. That makes it the choice for people who like a multi-cannabinoid oil and want no THC at all, for example because they are drug-tested at work.

We call our broad-spectrum oils "THC-free". They have a 0% THC specification, and their batch reports show THC as not detected. Lugano Clarity combines CBD and CBG, and Lucerne Calm combines CBD, CBG and CBDA. Our classic THC-free oils also keep other cannabinoids, such as CBG and CBC, as their reports on the test results page show.

Research on THC-free products is encouraging. In a 2025 study, 20 healthy adults took a commercial broad-spectrum CBD product by mouth every day for two weeks, about 34 mg of CBD a day. Neither THC nor its breakdown products could be detected in their urine at the end (Zvorsky et al., 2025). That study used another company's product, not ours. If testing is your main concern, our guide CBD and drug tests explains how tests work and what to choose.

What is CBD isolate?

CBD isolate is CBD purified from the other plant compounds. It is usually a white crystalline powder, which is then mixed into a carrier oil or another product. It contains no other cannabinoids and no terpenes.

People choose isolate when they want CBD and nothing else. In a controlled study, 100 mg of pure CBD, swallowed or vaporised, did not produce a confirmed positive urine test at standard workplace cut-offs (Spindle et al., 2020).

We don't make isolate oils. For customers who want no THC, we make THC-free broad-spectrum oils, which keep other cannabinoids as well as CBD.

What is in our oils? Cannabinoid profiles from our lab reports

This table shows the current batch reports for our four 30 ml blends. All four were analysed on 8 April 2026. The report shows each value after complete decarboxylation, so the CBDA in a formula is counted within the CBD figure.

Gas chromatograph with an autosampler tray of sample vials in Formula Swiss's lab
The profiles in this table were measured on equipment like this in our lab in Switzerland.
Cannabinoids in our 30 ml oils, % by weight (Formula Swiss certificates of analysis, report 260410_A01; sample ID in brackets). n.d. = not detected.
Oil (sample) Type CBD CBG CBC CBN Δ9-THC
St. Moritz Restore (260408.04) Full spectrum 25.13 4.29 1.51 0.13 0.14
Zermatt Balance (260408.03) Full spectrum 15.83 1.51 0.82 0.18 0.14
Lucerne Calm (260408.01) THC-free 20.50 3.19 n.d. n.d. n.d.
Lugano Clarity (260408.02) THC-free 10.47 7.28 n.d. n.d. n.d.
Cannabinoids other than CBD in our 30 ml oils (% by weight, THC not included)

Source: Formula Swiss certificates of analysis, report 260410_A01 (8 April 2026). Sum of CBG, CBC, CBN and CBDV.

The chart shows that "THC-free" does not have to mean "CBD only". Both types in our range carry other cannabinoids. The full-spectrum oils add the plant's natural THC trace and a wider mix, and the THC-free oils add CBG without THC.

Is full spectrum better than isolate? What the entourage effect research shows

The idea behind choosing full or broad spectrum is the "entourage effect": the theory that plant compounds work better together than alone. The research is still developing, and it points in more than one direction.

  • Where the term comes from. A research team in Jerusalem that included Raphael Mechoulam coined "entourage effect" in 1998. They found that fatty compounds in the body, which do nothing on their own, strengthened the effect of the body's own cannabinoid 2-AG (Ben-Shabat et al., 1998).
  • The plant hypothesis. A 2011 review proposed that cannabinoids such as CBD, CBG and CBC, and terpenes such as limonene, myrcene and linalool, may work together in cannabis extracts. The author also set out how such effects could be tested in future experiments (Russo, 2011).
  • An animal study. In mice, purified CBD worked best at a middle dose and less well at higher doses (a "bell-shaped" response). A CBD-rich plant extract gave a response that kept rising with the dose, and the authors suggest other components in the extract work with CBD (Gallily et al., 2015).
  • Observational data in people. A 2018 analysis pooled reports from 670 people with treatment-resistant epilepsy who used CBD products. People on CBD-rich extracts reached similar responder rates to those on purified CBD at about a quarter of the average dose: 6.0 against 25.3 mg per kg a day. (Responders had at least halved their seizures: 37% with extracts, 42% with purified CBD.) The extract group also reported improvement more often (71% against 46%) and reported side effects less often. The authors say controlled trials are needed to confirm the difference (Pamplona et al., 2018; doses as corrected in the corrigendum).
  • How it might work. Two laboratory studies tested common cannabis terpenes on the CB1 and CB2 cannabinoid receptors and found no direct effect, alone or combined with THC or CBD. The researchers conclude that if an entourage effect exists, it works through other targets in the body (Santiago et al., 2019; Finlay et al., 2020).

In short: there are promising signals for whole-plant extracts, and scientists are still working out how and when compounds combine. The studies above looked at other products, used in medical or laboratory settings. They do not describe our cosmetic oils, which are for use on the skin. For the full story, read our guide to the entourage effect.

Which should you choose?

  • You want the whole hemp profile: choose full spectrum. It keeps the plant's own cannabinoids, including its natural THC trace.
  • You want other cannabinoids but no THC: choose THC-free broad spectrum. This is also the simple choice if you are tested for drugs at work or at the roadside. See CBD and drug tests.
  • You compete in sport: WADA allows CBD, but prohibits all other natural and synthetic cannabinoids in competition (WADA Prohibited List 2026, S8). Full- and broad-spectrum oils both contain some, such as CBG. Check with your national anti-doping agency before using any cannabinoid product.
  • You want CBD and nothing else: that is isolate. We don't make isolate oils.

Talk to your doctor first

If you take medication, are pregnant or breastfeeding, or have liver problems, talk to your doctor before using any CBD product, whatever the type. See CBD side effects for more.

How can you check the type on a lab report?

A certificate of analysis (COA) lists the cannabinoids measured in one batch. To check the type:

Gas chromatography (GC-FID) chromatogram on a computer screen in Formula Swiss's lab
A GC-FID chromatogram from our lab. Each peak is a different compound; the certificate turns them into the percentages you see.
  1. Match the batch. The batch number on your bottle should match the report.
  2. Find the THC line. A full-spectrum oil shows a small Δ9-THC value. A THC-free oil shows "n.d." (not detected) or 0.00.
  3. Look for other cannabinoids. CBG, CBC or CBN values mean a full- or broad-spectrum oil. An isolate shows CBD and little else.
  4. Compare the CBD value with the label. It should be close to the stated percentage.

Every production batch is tested, and we publish the certificates of analysis on our test results page.

Frequently asked questions

Which is better, full spectrum or broad spectrum?

Neither is better for everyone. Full spectrum keeps the whole range of hemp cannabinoids, including a natural THC trace. Broad spectrum keeps several cannabinoids without THC. Choose full spectrum for the whole-plant profile, and THC-free broad spectrum if you want or need no THC.

Does broad-spectrum CBD contain THC?

No. Being THC-free is what sets it apart from full spectrum. Our THC-free oils have a 0% THC specification, and their batch reports show THC as not detected. With any brand, check the certificate of analysis for your batch.

How much THC is in full-spectrum CBD oil?

Only natural traces. Our full-spectrum oils have a THC specification under 0.2%, and the exact value for each batch is printed on the label and shown on its certificate of analysis.

Will full-spectrum CBD show up on a drug test?

Drug tests look for THC, not CBD. Full-spectrum products contain natural traces of THC, so if you are tested, the simple choice is a THC-free oil. Our guide to CBD and drug tests explains the details.

What is the difference between broad spectrum and isolate?

Both are THC-free. Broad spectrum also keeps other cannabinoids, such as CBG, CBC or CBN. Isolate is CBD on its own, with no other cannabinoids or terpenes.

What is the entourage effect?

It is the theory that cannabis compounds work better together than alone. Early studies, including observational data and animal research, point in that direction. Scientists are still working out how and when it happens.

Can athletes use full- or broad-spectrum CBD?

WADA allows CBD but prohibits all other cannabinoids in competition, and both full- and broad-spectrum oils contain some, such as CBG. Check with your national anti-doping agency before using any cannabinoid product.

This guide is general information, not medical advice. Our CBD oils are cosmetic products for use on the skin. They are not medicines and are not intended to diagnose, treat, cure or prevent any disease.

Last reviewed:

Sources

  1. Ben-Shabat S, Fride E, Sheskin T, et al. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Eur J Pharmacol 1998;353(1):23–31. doi:10.1016/s0014-2999(98)00392-6
  2. Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol 2011;163(7):1344–1364. doi:10.1111/j.1476-5381.2011.01238.x
  3. Gallily R, Yekhtin Z, Hanuš LO. Overcoming the bell-shaped dose-response of cannabidiol by using Cannabis extract enriched in cannabidiol. Pharmacology & Pharmacy 2015;6:75–85. doi:10.4236/pp.2015.62010
  4. Pamplona FA, da Silva LR, Coan AC. Potential clinical benefits of CBD-rich cannabis extracts over purified CBD in treatment-resistant epilepsy: observational data meta-analysis. Front Neurol 2018;9:759. doi:10.3389/fneur.2018.00759. Corrigendum: Front Neurol 2019;9:1050. doi:10.3389/fneur.2018.01050
  5. Santiago M, Sachdev S, Arnold JC, McGregor IS, Connor M. Absence of entourage: terpenoids commonly found in Cannabis sativa do not modulate the functional activity of Δ9-THC at human CB1 and CB2 receptors. Cannabis Cannabinoid Res 2019;4(3):165–176. doi:10.1089/can.2019.0016
  6. Finlay DB, Sircombe KJ, Nimick M, Jones C, Glass M. Terpenoids from cannabis do not mediate an entourage effect by acting at cannabinoid receptors. Front Pharmacol 2020;11:359. doi:10.3389/fphar.2020.00359
  7. Spindle TR, Cone EJ, Kuntz D, et al. Urinary pharmacokinetic profile of cannabinoids following administration of vaporized and oral cannabidiol and vaporized CBD-dominant cannabis. J Anal Toxicol 2020;44(2):109–125. doi:10.1093/jat/bkz080
  8. Zvorsky I, Kulpa J, Mechtler LL, et al. Urinalysis and perceived effects following 2-week use of a commercial broad-spectrum cannabidiol product. Exp Clin Psychopharmacol 2025;33(1):62–67. doi:10.1037/pha0000747
  9. Pavlovic R, Nenna G, Calvi L, et al. Quality traits of "cannabidiol oils": cannabinoids content, terpene fingerprint and oxidation stability of European commercially available preparations. Molecules 2018;23(5):1230. doi:10.3390/molecules23051230
  10. World Anti-Doping Agency. Prohibited List 2026, S8 Cannabinoids. wada-ama.org
  11. Formula Swiss. Certificates of analysis, report 260410_A01 (8 April 2026), and product pages for Zermatt Balance, St. Moritz Restore, Lugano Clarity and Lucerne Calm; test results. Checked 26 September 2026.
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Robin Roy Krigslund-Hansen

Robin Roy Krigslund-Hansen

Über den Autor

Robin Roy Krigslund-Hansen ist Gründer und CEO von Formula Swiss und für die Formulierung verantwortlich. Seit der Gründung des Unternehmens im Jahr 2013 schreibt er über Hanf, CBD und die Cannabisbranche. Seine Sichtweise stützt sich auf den Aufbau von Formula Swiss, Gespräche mit Forschenden und die Förderung der CBD-Forschung.

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